Circannual variation in the expression of β2-adrenoceptors on human peripheral mononuclear leukocytes (MNLs)
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چکیده
منابع مشابه
Beta 2-adrenoceptors in human lung and peripheral mononuclear leukocytes of untreated and terbutaline-treated patients.
Beta 2-adrenoceptor agonists act against bronchoconstriction by stimulating beta 2-adrenoceptors in bronchial smooth muscle. However, tachyphylaxis has been argued to occur because of beta 2-adrenoceptor down-regulation following therapy with beta 2-adrenergic agents. To investigate receptor alterations, human peripheral mononuclear leukocytes are frequently used, since human lung tissue is not...
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Normal variation in mononuclear cell gene expression Variation in gene expression profiles of peripheral blood mononuclear cells from healthy volunteers
The normal degree of intraand inter-individual variation in gene transcription profiles of healthy human tissues has not been extensively investigated. In the study described here, microarrays were employed to analyse gene transcription in peripheral blood mononuclear cells prepared from serial blood samples that had been obtained, at weekly intervals, from apparently healthy human volunteers. ...
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ژورنال
عنوان ژورنال: Klinische Wochenschrift
سال: 1988
ISSN: 0023-2173,1432-1440
DOI: 10.1007/bf01720832